Pentobarbital will minimize the extent or outcome of lopinavir by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch. Barbiturates can induce hepatic microsomal enzymes resulting in improved metabolism and decreased anticoagulant reaction of oral anticoagulants (eg, warfarin, acenocoumarol, dicumarol, and phenprocoumon); clients stabilized on anticoagulant therap... https://isnembutalabarbiturate15824.bloggerbags.com/36159277/is-nembutal-a-depressant-an-overview