Pentobarbital raises toxicity of buprenorphine, very long-acting injection by pharmacodynamic synergism. Modify Therapy/Observe Closely. Coadministration of buprenorphine and benzodiazepines or other CNS depressants increases danger of adverse reactions which includes overdose, respiratory despair, and Demise. Cessation of benzodiazepines or other CNS depressants is most popular most ... https://pikq886gwl4.wikiparticularization.com/user