Lousy/Extensive Metabolizers, CYP2D6 The formation from the Lively metabolite, M1, is mediated by CYP2D6, a polymorphic enzyme. Approximately seven% from the inhabitants has lessened exercise from the CYP2D6 isoenzyme of cytochrome P450 metabolizing enzyme procedure. These individuals are “very poor metabolizers” of debrisoquine, dextromethorphan and tricyclic antidepressants, between... https://anneb208cin2.wonderkingwiki.com/user